Maryland's Defense Patent Database

The defense community in Maryland is an R&D powerhouse. Use this database to see the innovative patents that are poised for commercialization.

Data is provided by DoD Naval labs in Southern Maryland. Database funding supported by the DoD Office of Economic Adjustment through a Defense Industry Adjustment grant program.

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Modular linkers for conjugation of organic substances to substantially inorganic substances and methods of manufacture and use thereof

Patent Number: 9,139,614

AbstractA modular linker includes an inorganic binding entity having an affinity for a substantially inorganic substance, and an organic binding entity capable of binding with an organic substance covalently bonded thereto. The modular linker is capable of being stored in a stable condition for later use. The modular linker may be synthesized by modifying the inorganic binding entity to be covalently bonded to an organic binding entity and storing the modular linker in an inert environment from about a day up to at least 1 week. The modular linker may be conjugated to an organic substance and to a substantially inorganic substance in substantially a 1:1 ratio. The modular linker may have more than one organic binding entity covalently bonded to an inorganic binding entity or vice-versa. Also, a particular modular linker may have an organic binding entity capable of binding with a nucleic acid sequence.
Patent Number9,139,614 Issue Date2015-09-22 Link USPTO website

Primary Category

Biographical Information


  • Igor L. Medintz,
  • Lorenzo Berti,
  • Paolo Facci,
  • Hedi M. Mattoussi,


  • The United States of America, as represented by the Secretary of the Navy

Executive Summary

This patent was granted in 8 years, 152 days, which is a much slower than average speed.

It has 26 claims, which is fewer than average for this category.

Its proximity to basic research is much less than others in this category, and it displays a much slower than average technology cycle time.

This patent received far fewer citations from other patents, and references far fewer other patents, as compared to other patents in this category.

Grant Time

8 years, 152 days



Patent Grant Time

This patent had a much slower than average grant time compared to others in this category.

Patent grant time can be influenced by many factors. Activities within the USPTO that are beyond the control of patent attornies can influence grant time, but short grant times can also indicate well-written patents and dedicated efforts to respond rapidly to USPTO office actions with strong arguments. Shorter grant times are preferable, and the scores for this section are inverse measures — higher scores are better.

Patent Claims

This patent has fewer claims compared to others in this category.

The number of claims in a patent is correlated with its strength. Because greater claim counts increase the cost of a patent, more claims can indicate the importance an applicant assigns to a patent. Importantly, some may elect to file claims across multiple patents. A higher score in this metric indicates more claims, relative to others in this category.

Citations From Other Patents

This patent has received far fewer citations from other patents, than others in this category.

Citations from other patents are an important measure of the significance of a patent. More citations indicate that other technologies build on a patent. Higher scores in this metric are better, and indicate more citations from other patents.

Citations to Other Patents

This patent referenced many more citations to other patents, than others in this category.

A lower number of citations to other patents can be a sign of diminished patent strength. More citations indicate dependence on more other technologies. Higher scores in this category are better, and indicate fewer citations to other patents.

Research and Innovation Indicators
These are percentile ranks — they indicate the percentage of peers with lower scores.

Proximity to Basic Research



This patent has much less proximity to basic research compared to others in this category.

Proximity to basic research is measured by comparing the number of citations to non-patent literature among a cohort of patents. Because most non-patent citations are primary research papers, a higher count indicates greater proximity to basic research.